Capacity for stochastic self-renewal and differentiation in mammalian spermatogonial stem cells

Mammalian spermatogenesis is initiated and sustained by spermatogonial stem cells (SSCs) through self-renewal and differentiation. The basic question of whether SSCs have the potential to specify self-renewal and differentiation in a cell-autonomous manner has yet to be addressed. Here, we show that...

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Bibliographic Details
Main Authors: Wu, Zhuoru, Luby-Phelps, Katherine, Bugde, Abhijit, Molyneux, Laura A., Denard, Bray, Li, Wen-Hong, Süel, Gürol M., Garbers, David L.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2009
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779229/
https://ncbi.nlm.nih.gov/pubmed/19948499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200907047
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