ALDH1A2 (RALDH2) genetic variation in human congenital heart disease

BACKGROUND: Signaling by the vitamin A-derived morphogen retinoic acid (RA) is required at multiple steps of cardiac development. Since conversion of retinaldehyde to RA by retinaldehyde dehydrogenase type II (ALDH1A2, a.k.a RALDH2) is critical for cardiac development, we screened patients with cong...

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Bibliografische gegevens
Hoofdauteurs: Pavan, Marilene, Ruiz, Viviane F, Silva, Fábio A, Sobreira, Tiago J, Cravo, Roberta M, Vasconcelos, Michelle, Marques, Lívia P, Mesquita, Sonia MF, Krieger, José E, Lopes, Antônio AB, Oliveira, Paulo S, Pereira, Alexandre C, Xavier-Neto, José
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2009
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Research article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779186/
https://ncbi.nlm.nih.gov/pubmed/19886994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-10-113
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