ALDH1A2 (RALDH2) genetic variation in human congenital heart disease

BACKGROUND: Signaling by the vitamin A-derived morphogen retinoic acid (RA) is required at multiple steps of cardiac development. Since conversion of retinaldehyde to RA by retinaldehyde dehydrogenase type II (ALDH1A2, a.k.a RALDH2) is critical for cardiac development, we screened patients with cong...

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Detalhes bibliográficos
Main Authors: Pavan, Marilene, Ruiz, Viviane F, Silva, Fábio A, Sobreira, Tiago J, Cravo, Roberta M, Vasconcelos, Michelle, Marques, Lívia P, Mesquita, Sonia MF, Krieger, José E, Lopes, Antônio AB, Oliveira, Paulo S, Pereira, Alexandre C, Xavier-Neto, José
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779186/
https://ncbi.nlm.nih.gov/pubmed/19886994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-10-113
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