Application of an integrated physical and functional screening approach to identify inhibitors of the Wnt pathway

Large-scale proteomic approaches have been used to study signaling pathways. However, identification of biologically relevant hits from a single screen remains challenging due to limitations inherent in each individual approach. To overcome these limitations, we implemented an integrated, multi-dime...

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Detalhes bibliográficos
Main Authors: Miller, Bryan W, Lau, Garnet, Grouios, Chris, Mollica, Emanuela, Barrios-Rodiles, Miriam, Liu, Yongmei, Datti, Alessandro, Morris, Quaid, Wrana, Jeffrey L, Attisano, Liliana
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779086/
https://ncbi.nlm.nih.gov/pubmed/19888210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2009.72
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