Macrophage Activation Syndrome in Systemic Juvenile Idiopathic Arthritis is Associated With MUNC13-4 Gene Polymorphisms

OBJECTIVE: Systemic Juvenile Idiopathic Arthritis (SJIA) is associated with macrophage activation syndrome (MAS). MAS bears close resemblance to familial hemophagocytic lymphohistiocytosis (FHLH). The development of FHLH has been recently associated with mutations in MUNC13-4 gene. The purpose of th...

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Principais autores: Zhang, Kejian, Biroschak, Jennifer, Glass, David N., Thompson, Susan, Finkel, Terri, Passo, Murray H., Binstadt, Bryce A., Filipovich, Alexandra, Grom, Alexei A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779064/
https://ncbi.nlm.nih.gov/pubmed/18759271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.23734
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