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Allelic Variation of Ets1 Does Not Contribute to NK and NKT Cell Deficiencies in Type 1 Diabetes Susceptible NOD Mice

The NOD mouse is a well characterized model of type 1 diabetes that shares several of the characteristics of Ets1-deficient targeted mutant mice, viz: defects in TCR allelic exclusion, susceptibility to a lupus like disease characterized by IgM and IgG autoantibodies and immune complex-mediated glom...

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Detalhes bibliográficos
Main Authors: Jordan, Margaret A., Poulton, Lynn D., Fletcher, Julie M., Baxter, Alan G.
Formato: Artigo
Idioma:Inglês
Publicado em: SBDR - Society for Biomedical Diabetes Research 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779013/
https://ncbi.nlm.nih.gov/pubmed/19806240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1900/RDS.2009.6.104
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