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Cross-Species RNAi Rescue Platform in Drosophila melanogaster
RNAi-mediated gene knockdown in Drosophila melanogaster is a powerful method to analyze loss-of-function phenotypes both in cell culture and in vivo. However, it has also become clear that false positives caused by off-target effects are prevalent, requiring careful validation of RNAi-induced phenot...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Genetics Society of America
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2778968/ https://ncbi.nlm.nih.gov/pubmed/19720858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.109.106567 |
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