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Cross-Species RNAi Rescue Platform in Drosophila melanogaster

RNAi-mediated gene knockdown in Drosophila melanogaster is a powerful method to analyze loss-of-function phenotypes both in cell culture and in vivo. However, it has also become clear that false positives caused by off-target effects are prevalent, requiring careful validation of RNAi-induced phenot...

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Autors principals: Kondo, Shu, Booker, Matthew, Perrimon, Norbert
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778968/
https://ncbi.nlm.nih.gov/pubmed/19720858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.109.106567
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