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Chromatin Regulation and Gene Centrality Are Essential for Controlling Fitness Pleiotropy in Yeast

BACKGROUND: There are a wide range of phenotypes that are due to loss-of-function or null mutations. Previously, the functions of gene products that distinguish essential from nonessential genes were characterized. However, the functions of products of non-essential genes that contribute to fitness...

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Autors principals: Zhou, Linqi, Ma, Xiaotu, Arbeitman, Michelle N., Sun, Fengzhu
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778950/
https://ncbi.nlm.nih.gov/pubmed/19956643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008086
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