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PPARγ Regulates Trophoblast Proliferation and Promotes Labyrinthine Trilineage Differentiation
BACKGROUND: Abnormal trophoblast differentiation and function is the basis of many placenta-based pregnancy disorders, including pre-eclampsia and fetal growth restriction. PPARγ, a ligand-activated nuclear receptor, plays essential roles in placental development; null murine embryos die at midgesta...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2778869/ https://ncbi.nlm.nih.gov/pubmed/19956639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008055 |
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