PPARγ Regulates Trophoblast Proliferation and Promotes Labyrinthine Trilineage Differentiation

BACKGROUND: Abnormal trophoblast differentiation and function is the basis of many placenta-based pregnancy disorders, including pre-eclampsia and fetal growth restriction. PPARγ, a ligand-activated nuclear receptor, plays essential roles in placental development; null murine embryos die at midgesta...

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Autors principals: Parast, Mana M., Yu, Heather, Ciric, Aleksandar, Salata, Mark W., Davis, Vannessa, Milstone, David S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778869/
https://ncbi.nlm.nih.gov/pubmed/19956639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008055
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