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Ras pathway activation in gliomas: a strategic target for intranasal administration of perillyl alcohol
INTRODUCTION: Targeted therapy directed at specific molecular alterations is already creating a shift in the treatment of cancer patients. Malignant gliomas commonly overexpress the oncogenes EGFR and PDGFR and contain mutations and deletions of the tumor suppressor genes PTEN and TP53. Some of thes...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Birkhäuser-Verlag
2008
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2778682/ https://ncbi.nlm.nih.gov/pubmed/18726148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00005-008-0027-0 |
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