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Ras pathway activation in gliomas: a strategic target for intranasal administration of perillyl alcohol
INTRODUCTION: Targeted therapy directed at specific molecular alterations is already creating a shift in the treatment of cancer patients. Malignant gliomas commonly overexpress the oncogenes EGFR and PDGFR and contain mutations and deletions of the tumor suppressor genes PTEN and TP53. Some of thes...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Birkhäuser-Verlag
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2778682/ https://ncbi.nlm.nih.gov/pubmed/18726148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00005-008-0027-0 |
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