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A Noisy Paracrine Signal Determines the Cellular NF-κB Response to Lipopolysaccharide
Nearly identical cells can exhibit substantially different responses to the same stimulus. We monitored the nuclear localization dynamics of nuclear factor κB (NF-κB) in single cells stimulated with tumor necrosis factor-α (TNF-α) and lipopolysaccharide (LPS). Cells stimulated with TNF-α have quanti...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2778577/ https://ncbi.nlm.nih.gov/pubmed/19843957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000599 |
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