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DEOXYRIBONUCLEASE IV: A NEW EXONUCLEASE FROM MAMMALIAN TISSUES

An exonuclease which specifically degrades double-standard DNA has been isolated from rabbit tissues. The enzyme has an approximate molecular weight of 42,000, requires a divalent metal ion as cofactor, and attacks DNA at the 5′-terminal ends, thereby liberating 5′-mononucleotides. It degrades sever...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Lindahl, Tomas, Gally, Joseph A., Edelman, Gerald M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1969
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC277851/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5256235/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.62.2.597
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