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DEOXYRIBONUCLEASE IV: A NEW EXONUCLEASE FROM MAMMALIAN TISSUES

An exonuclease which specifically degrades double-standard DNA has been isolated from rabbit tissues. The enzyme has an approximate molecular weight of 42,000, requires a divalent metal ion as cofactor, and attacks DNA at the 5′-terminal ends, thereby liberating 5′-mononucleotides. It degrades sever...

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Detalles Bibliográficos
Main Authors: Lindahl, Tomas, Gally, Joseph A., Edelman, Gerald M.
Formato: Artigo
Idioma:Inglês
Publicado: 1969
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC277851/
https://ncbi.nlm.nih.gov/pubmed/5256235
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