Загрузка...
FOXP3 Inhibits Activation-Induced NFAT2 Expression in T Cells Thereby Limiting Effector Cytokine Expression
The forkhead DNA-binding protein FOXP3 is critical for the development and suppressive function of CD4(+)CD25(+) regulatory T cells (T(REG)), which play a key role in maintaining self-tolerance. Functionally, FOXP3 is capable of repressing transcription of cytokine genes regulated by the Nuclear Fac...
Сохранить в:
| Главные авторы: | , , , , , , , , , , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2778477/ https://ncbi.nlm.nih.gov/pubmed/19564342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0800216 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|