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Neutrophil-mediated Activation of Epithelial Protease-Activated Receptors-1 and -2 Regulates Barrier Function and Transepithelial Migration

Neutrophil (PMN) infiltration and associated release of serine proteases contribute to epithelial injury during active phases of mucosal disorders such as inflammatory bowel disease. Previous studies have demonstrated that PMN contact with basolateral surfaces of intestinal epithelial cells in the p...

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Detalhes bibliográficos
Main Authors: Chin, Alex C., Lee, Winston Y., Nusrat, Asma, Vergnolle, Nathalie, Parkos, Charles A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778473/
https://ncbi.nlm.nih.gov/pubmed/18832729
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