EFFECT OF GM-CSF ON CIRCULATING CD8(+) AND CD4(+) T CELL RESPONSES TO A MULTIPEPTIDE MELANOMA VACCINE: OUTCOME OF A MULTICENTER RANDOMIZED TRIAL

PURPOSE: GM-CSF administered locally together with vaccines can augment T cell responses in animal models. Human experience has been limited to small and uncontrolled trials. Thus, a multicenter randomized phase II trial was performed to determine whether local administration of GM-CSF augments immu...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Slingluff, Craig L., Petroni, Gina R., Olson, Walter C., Smolkin, Mark E., Ross, Merrick I., Haas, Naomi B., Grosh, William W., Boisvert, Marc E, Kirkwood, John M., Chianese-Bullock, Kimberly A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778314/
https://ncbi.nlm.nih.gov/pubmed/19903780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-1544
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi