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Kinesin-5 in Drosophila Embryo Mitosis: Sliding Filament or Spindle Matrix Mechanism?

The Drosophila syncytial embryo uses multiple astral mitotic spindles that are specialized for rapid mitosis. The homotetrameric kinesin-5, KLP61F contributes to various aspects of mitosis in this system, all of which are consistent with it exerting outward forces on spindle poles. In principle, kin...

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Bibliographic Details
Main Author: Scholey, Jonathan M.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778298/
https://ncbi.nlm.nih.gov/pubmed/19291760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cm.20349
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