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Reverse engineering of force integration during mitosis in the Drosophila embryo

Abstract The mitotic spindle is a complex macromolecular machine that coordinates accurate chromosome segregation. The spindle accomplishes its function using forces generated by microtubules (MTs) and multiple molecular motors, but how these forces are integrated remains unclear, since the temporal...

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Bibliographic Details
Main Authors: Roy Wollman, Gul Civelekoglu‐Scholey, Jonathan M Scholey, Alex Mogilner
Format: Artigo
Language:Inglês
Published: Springer Nature 2008-05-01
Series:Molecular Systems Biology
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Online Access:https://doi.org/10.1038/msb.2008.23
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