Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium

Erythrocyte measures are heritable and have important health implications, yet their genetic determinants are largely unknown. We performed genome-wide association analyses in 24,167 European-ancestry individuals for six erythrocyte traits and identified associations at 23 loci (P values 5×10(-8) to...

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Main Authors: Ganesh, Santhi K., Zakai, Neil A., van Rooij, Frank J A., Soranzo, Nicole, Smith, Albert V., Nalls, Michael A., Chen, Ming-Huei, Kottgen, Anna, Glazer, Nicole L., Dehghan, Abbas, Kuhnel, Brigitte, Aspelund, Thor, Yang, Qiong, Tanaka, Toshiko, Jaffe, Andrew, Bis, Joshua C M., Verwoert, Germaine C., Teumer, Alexander, Fox, Caroline S., Guralnik, Jack M., Ehret, Georg B., Rice, Kenneth, Felix, Janine F., Rendon, Augusto, Eiriksdottir, Gudny, Levy, Daniel, Patel, Kushang V., Boerwinkle, Eric, Rotter, Jerome I., Hofman, Albert, Sambrook, Jennifer G., Hernandez, Dena, Zheng, Gang, Bandinelli, Stefania, Singleton, Andrew B., Coresh, Josef, Lumley, Thomas, Uitterlinden, André G., vanGils, Janine M., Launer, Lenore J., Cupples, L. Adrienne, Oostra, Ben A., Zwaginga, Jaap-Jan, Ouwehand, Willem H., Thein, Swee-Lay, Meisinger, Christa, Deloukas, Panos, Nauck, Matthias, Spector, Tim, Gieger, Christian, Gudnason, Vilmundur, van Duijn, Cornelia M., Psaty, Bruce M., Ferrucci, Luigi, Chakravarti, Aravinda, Greinacher, Andreas, O’Donnell, Christopher J., Witteman, Jacqueline C M., Furth, Susan, Cushman, Mary, Harris, Tamara B., Lin, Jing-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778265/
https://ncbi.nlm.nih.gov/pubmed/19862010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.466
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