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Alterations of the Thioredoxin System by Hyperoxia: Implications for Alveolar Development

Alterations in vascular endothelial growth factor (VEGF) contribute to alveolar simplification seen in animal models of bronchopulmonary dysplasia, and VEGF expression is redox regulated by thioredoxin (Trx)-1 in other diseases. The present studies tested the hypothesis that exposure to 85% O(2) neg...

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Bibliographic Details
Main Authors: Tipple, Trent E., Welty, Stephen E., Nelin, Leif D., Hansen, Jason M., Rogers, Lynette K.
Format: Artigo
Language:Inglês
Published: American Thoracic Society 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778167/
https://ncbi.nlm.nih.gov/pubmed/19244202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0224OC
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