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The ATM and ATR inhibitors CGK733 and caffeine suppress cyclin D1 levels and inhibit cell proliferation

The ataxia telangiectasia mutated (ATM) and the ATM- related (ATR) kinases play a central role in facilitating the resistance of cancer cells to genotoxic treatment regimens. The components of the ATM and ATR regulated signaling pathways thus provide attractive pharmacological targets, since their i...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Alao, John P, Sunnerhagen, Per
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777912/
https://ncbi.nlm.nih.gov/pubmed/19903334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-4-51
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