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Synthesis and Structural Characterization of Carboxyethylpyrrole-Modified Proteins: Mediators of Age-related Macular Degeneration

[Image: see text] Protein modifications in which the ε-amino group of lysyl residues is incorporated into a 2-(ω-carboxyethyl)pyrrole (CEP) are mediators of age-related macular degeneration (AMD). They promote both angiogenesis into the retina (“wet AMD”) and geographic retinal atrophy (“dry AMD”)....

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Autors principals: Lu, Liang, Gu, Xiaorong, Hong, Li, Laird, James, Jaffe, Keeve, Choi, Jaewoo, Crabb, John, Salomon, Robert G.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777691/
https://ncbi.nlm.nih.gov/pubmed/19786352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.09.009
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