Investigating the role of the interleukin-23/-17A axis in rheumatoid arthritis

Objective. IL-23 is a pro-inflammatory cytokine proposed to be central to the development of autoimmune disease. We investigated whether IL-23, together with the downstream mediator IL-17A, was present and functional in RA in humans. Methods. RA synovial cells were cultured in the presence or absenc...

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Main Authors:	Hillyer, Philippa, Larché, Maggie J., Bowman, Edward P., McClanahan, Terrill K., de Waal Malefyt, Rene, Schewitz, Lauren P., Giddins, Grey, Feldmann, Marc, Kastelein, Robert A., Brennan, Fionula M.
Format:	Artigo
Language:	Inglês
Published:	Oxford University Press 2009
Subjects:	Clinical
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2777488/ https://ncbi.nlm.nih.gov/pubmed/19815670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/kep293
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Investigating the role of the interleukin-23/-17A axis in rheumatoid arthritis

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