Protease activation during in vivo pancreatitis is dependent on calcineurin activation

The premature activation of digestive proenzymes, specifically proteases, within the pancreatic acinar cell is an early and critical event during acute pancreatitis. Our previous studies demonstrate that this activation requires a distinct pathological rise in cytosolic Ca(2+). Furthermore, we have...

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Detalhes bibliográficos
Main Authors: Shah, Ahsan U., Sarwar, Amna, Orabi, Abrahim I., Gautam, Samir, Grant, Wayne M., Park, Alexander J., Shah, Adnan U., Liu, Jun, Mistry, Pramod K., Jain, Dhanpat, Husain, Sohail Z.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Hormones and Signaling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777459/
https://ncbi.nlm.nih.gov/pubmed/20501444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00181.2009
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