Involvement of p54(nrb), a PSF partner protein, in DNA double-strand break repair and radioresistance

Mammalian cells repair DNA double-strand breaks (DSBs) via efficient pathways of direct, nonhomologous DNA end joining (NHEJ) and homologous recombination (HR). Prior work has identified a complex of two polypeptides, PSF and p54(nrb), as a stimulatory factor in a reconstituted in vitro NHEJ system....

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Autores principales: Li, Shuyi, Kuhne, Wendy W., Kulharya, Anita, Hudson, Farlyn Z., Ha, Kyungsoo, Cao, Zhen, Dynan, William S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2009
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777424/
https://ncbi.nlm.nih.gov/pubmed/19759212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp741
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