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Loss of the apical V-ATPase a-subunit VHA-6 prevents acidification of the intestinal lumen during a rhythmic behavior in C. elegans

In Caenorhabditis elegans, oscillations of intestinal pH contribute to the rhythmic defecation behavior, but the acid-base transport mechanisms that facilitate proton movement are not well understood. Here, we demonstrate that VHA-6, an intestine-specific a-subunit of the H(+)-K(+)-ATPase complex (V...

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Hlavní autoři: Allman, Erik, Johnson, David, Nehrke, Keith
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777397/
https://ncbi.nlm.nih.gov/pubmed/19741196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00284.2009
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