Closed-state inactivation in Kv4.3 isoforms is differentially modulated by protein kinase C

Kv4.3, with its complex open- and closed-state inactivation (CSI) characteristics, is a primary contributor to early cardiac repolarization. The two alternatively spliced forms, Kv4.3-short (Kv4.3-S) and Kv4.3-long (Kv4.3-L), differ by the presence of a 19-amino acid insert downstream from the sixth...

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Detalhes bibliográficos
Main Authors: Xie, Chang, Bondarenko, Vladimir E., Morales, Michael J., Strauss, Harold C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Membrane Transporters, Ion Channels, and Pumps
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777396/
https://ncbi.nlm.nih.gov/pubmed/19675305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00144.2009
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