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The L49F mutation in alpha erythroid spectrin induces local disorder in the tetramer association region: Fluorescence and molecular dynamics studies of free and bound alpha spectrin

The bundling of the N-terminal, partial domain helix (Helix C′) of human erythroid α-spectrin (αI) with the C-terminal, partial domain helices (Helices A′ and B′) of erythroid β-spectrin (βI) to give a spectrin pseudo structural domain (triple helical bundle A′B′C′) has long been recognized as a cru...

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Autori principali: Song, Yuanli, Pipalia, Nina H, Fung, L W-M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley Subscription Services, Inc., A Wiley Company 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777366/
https://ncbi.nlm.nih.gov/pubmed/19593814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.202
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