The Specificity of the FOXL2 c.402C>G Somatic Mutation: A Survey of Solid Tumors

BACKGROUND: A somatic mutation in the FOXL2 gene is reported to be present in almost all (97%; 86/89) morphologically defined, adult-type, granulosa-cell tumors (A-GCTs). This FOXL2 c.402C>G mutation changes a highly conserved cysteine residue to a tryptophan (p.C134W). It was also found in a min...

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Hlavní autoři: Schrader, Kasmintan A., Gorbatcheva, Bella, Senz, Janine, Heravi-Moussavi, Alireza, Melnyk, Nataliya, Salamanca, Clara, Maines-Bandiera, Sarah, Cooke, Susanna L., Leung, Peter, Brenton, James D., Gilks, C. Blake, Monahan, John, Huntsman, David G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777318/
https://ncbi.nlm.nih.gov/pubmed/19956657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007988
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