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Sex hormones and leflunomide treatment of human macrophage cultures: effects on apoptosis

In order to establish the possible gender influence on the activity of leflunomide (LEF) in rheumatoid arthritis (RA), we evaluated the proapoptotic activity of the active LEF metabolite A77 1726 (LEF-M), in combination with sex hormones, on cultures of human macrophages. In particular, we focussed...

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Détails bibliographiques
Auteurs principaux: Montagna, Paola, Brizzolara, Renata, Soldano, Stefano, Pizzorni, Carmen, Sulli, Alberto, Cutolo, Maurizio
Format: Artigo
Langue:Inglês
Publié: e-Century Publishing Corporation 2009
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777270/
https://ncbi.nlm.nih.gov/pubmed/19918315
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