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Purification, crystallization and preliminary X-ray diffraction analysis of disease-related mutants of p97
The human type II AAA+ protein p97 participates in various cellular activities, presumably through its involvement in the ubiquitin–proteasome degradation pathway. Mutations in p97 have been implicated in patients with inclusion-body myopathy associated with Paget’s disease of the bone and frontotem...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
International Union of Crystallography
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2777050/ https://ncbi.nlm.nih.gov/pubmed/19923742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S174430910904055X |
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