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Polymorphisms in the CD28/CTLA4/ICOS genes: role in malignant melanoma susceptibility and prognosis?

The appearance of vitiligo and spontaneous regression of the primary lesion in melanoma patients illustrate a relationship between tumor immunity and autoimmunity. T lymphocytes play a major role both in tumor immunity and autoimmunity. CD28, Cytotoxic T lymphocyte antigen 4 (CTLA4) and inducible co...

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Detalhes bibliográficos
Main Authors: Bouwhuis, Marna G., Gast, Andreas, Figl, Adina, Eggermont, Alexander M. M., Hemminki, Kari, Schadendorf, Dirk, Kumar, Rajiv
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776942/
https://ncbi.nlm.nih.gov/pubmed/19672595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-009-0751-2
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