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Pathophysiology of Hypertension in Response to Placental Ischemia during Pregnancy: A Central Role for Endothelin?

BACKGROUND: Preeclampsia is new onset hypertension during pregnancy with proteinuria. The initiating event in preeclampsia has been postulated to involve reduce placental perfusion which leads to widespread dysfunction of the maternal vascular endothelium. OBJECTIVE: The main objective of this brief...

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Detalhes bibliográficos
Main Authors: LaMarca, Babbette D., Alexander, Barbara T., Gilbert, Jeffery S., Ryan, Michael J., Sedeek, Mona, Murphy, Sydney R., Granger, Joey P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776712/
https://ncbi.nlm.nih.gov/pubmed/18395679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.genm.2008.03.013
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