Discovery, Characterization and Comparison of Inhibitors of Bacillus anthracis and Staphylococcus aureus Replicative DNA Helicases

Antibacterial compounds with new mechanisms of action are needed for effective therapy against drug-resistant pathogens in the clinic and in biodefense. Screens for inhibitors of the essential replicative helicases of Bacillus anthracis and Staphylococcus aureus yielded 18 confirmed hits (IC(50) ≤ 2...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Aiello, Daniel, Barnes, Marjorie H., Biswas, Esther E., Biswas, Subhasis B., Gu, Shen, Williams, John D., Bowlin, Terry L., Moir, Donald T.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776654/
https://ncbi.nlm.nih.gov/pubmed/19477652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.05.014
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares