Capturing a Flavivirus Pre-Fusion Intermediate

During cell entry of flaviviruses, low endosomal pH triggers the rearrangement of the viral surface glycoproteins to a fusion-active state that allows the release of the infectious RNA into the cytoplasm. In this work, West Nile virus was complexed with Fab fragments of the neutralizing mAb E16 and...

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Bibliographische Detailangaben
Hauptverfasser: Kaufmann, Bärbel, Chipman, Paul R., Holdaway, Heather A., Johnson, Syd, Fremont, Daved H., Kuhn, Richard J., Diamond, Michael S., Rossmann, Michael G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2009
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776511/
https://ncbi.nlm.nih.gov/pubmed/19956725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000672
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