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Studies of haspin-depleted cells reveal that spindle-pole integrity in mitosis requires chromosome cohesion

Cohesins and their regulators are vital for normal chromosome cohesion and segregation. A number of cohesion proteins have also been localized to centrosomes and proposed to function there. We show that RNAi-mediated depletion of factors required for cohesion, including haspin, Sgo1 and Scc1, leads...

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Hlavní autoři: Dai, Jun, Kateneva, Anna V., Higgins, Jonathan M. G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Company of Biologists 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776503/
https://ncbi.nlm.nih.gov/pubmed/19910498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.054122
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