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Copper-Mediated Amidation of Heterocyclic and Aromatic C−H Bonds

[Image: see text] A copper-mediated aerobic coupling reaction enables direct amidation of heterocycles or aromatics having weakly acidic C−H bonds with a variety of nitrogen nucleophiles. These reactions provide efficient access to many biologically important skeletons, including ones with the poten...

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Detalhes bibliográficos
Main Authors: Wang, Qiu, Schreiber, Stuart L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2009
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776381/
https://ncbi.nlm.nih.gov/pubmed/19860425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol902079g
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