Mutations in the Human naked cuticle Homolog NKD1 Found in Colorectal Cancer Alter Wnt/Dvl/β-Catenin Signaling

BACKGROUND: Mutation of Wnt signal antagonists Apc or Axin activates β-catenin signaling in many cancers including the majority of human colorectal adenocarcinomas. The phenotype of apc or axin mutation in the fruit fly Drosophila melanogaster is strikingly similar to that caused by mutation in the...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Guo, Jianhui, Cagatay, Tolga, Zhou, Guangjin, Chan, Chih-Chiang, Blythe, Shelby, Suyama, Kaye, Zheng, Li, Pan, Kaifeng, Qian, Chiping, Hamelin, Richard, Thibodeau, Stephen N., Klein, Peter S., Wharton, Keith A., Liu, Wanguo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2009
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776356/
https://ncbi.nlm.nih.gov/pubmed/19956716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007982
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk