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Overcoming cancer therapy resistance by targeting inhibitors of apoptosis proteins and nuclear factor-kappa B

Chemo- or radioresistance markedly impairs the efficacy of cancer therapy and involves anti-apoptotic signal transduction pathways that prevent cell death. In resistant cancer cells, both inhibitors of apoptosis proteins (IAPs) and nuclear factor-kappa B (NF-κB) play a pivotal role in preventing apo...

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Hlavní autoři: Dai, Yao, Lawrence, Theodore S., Xu, Liang
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776288/
https://ncbi.nlm.nih.gov/pubmed/19966933
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