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The Fitness Effects of Random Mutations in Single-Stranded DNA and RNA Bacteriophages

Mutational fitness effects can be measured with relatively high accuracy in viruses due to their small genome size, which facilitates full-length sequencing and genetic manipulation. Previous work has shown that animal and plant RNA viruses are very sensitive to mutation. Here, we characterize mutat...

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Bibliografske podrobnosti
Main Authors: Domingo-Calap, Pilar, Cuevas, José M., Sanjuán, Rafael
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776273/
https://ncbi.nlm.nih.gov/pubmed/19956760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000742
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