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A temperature sensitive mutant of heat shock protein 70 reveals an essential role during the early steps of tombusvirus replication

By co-opting host proteins for their replication, plus-stranded RNA viruses can support robust replication and suppress host anti-viral responses. Tomato bushy stunt tombusvirus (TBSV) recruit the cellular heat shock protein 70 (Hsp70), an abundant cytosolic chaperone, into the replicase complex. By...

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Detalhes bibliográficos
Main Authors: Wang, Robert Yung-Liang, Stork, Jozsef, Pogany, Judit, Nagy, Peter D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776036/
https://ncbi.nlm.nih.gov/pubmed/19748649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.08.003
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