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Activation of Tomato Bushy Stunt Virus RNA-Dependent RNA Polymerase by Cellular Heat Shock Protein 70 Is Enhanced by Phospholipids In Vitro

Similar to other positive-strand RNA viruses, tombusviruses are replicated by the membrane-bound viral replicase complex (VRC). The VRC consists of the p92 virus-coded RNA-dependent RNA polymerase (RdRp), the viral p33 RNA chaperone, and several co-opted host proteins. In order to become a functiona...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Pogany, Judit, Nagy, Peter D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442504/
https://ncbi.nlm.nih.gov/pubmed/25762742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03711-14
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