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Global Disturbances in Autonomic Function Yield Cardiovascular Instability and Hypertension in the Chromogranin A Null Mouse

We reported previously that chromogranin A (Chga) knockout (KO) mice are hypertensive and hyperadrenergic. Here we sought to determine the basis of such alterations by probing physiological, biochemical, and pharmacological responses to perturbations of the autonomic nervous system. In the conscious...

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Bibliographic Details
Main Authors: Gayen, Jiaur R., Gu, Yusu, O'Connor, Daniel T., Mahata, Sushil K.
Format: Artigo
Language:Inglês
Published: The Endocrine Society 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775982/
https://ncbi.nlm.nih.gov/pubmed/19819970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-0429
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