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Release and Activity of Anti-TNFα Therapeutics from Injectable Chitosan Preparations for Local Drug Delivery
BACKGROUND: Tumor necrosis factor alpha (TNFα) is a cytokine that regulates immune and inflammatory overactivation in various pathological states. Protein therapeutics may antagonize this cytokine, but may also have systemic toxicities. Small molecule natural products are also efficacious, but can s...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2775925/ https://ncbi.nlm.nih.gov/pubmed/19072988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.b.31289 |
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