Interleukin-17 synergizes with IFNγ or TNFα to promote inflammatory mediator release and intercellular adhesion molecule-1 (ICAM-1) expression in human intervertebral disc cells

Interleukin-17 (IL-17) is a cytokine recently shown to be elevated, along with interferon-γ (IFNγ) and tumor necrosis factor (TNFα), in degenerated and herniated intervertebral disc (IVD) tissues, suggesting a role for these cytokines in intervertebral disc disease. The objective of our study was to...

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Detalhes bibliográficos
Main Authors: Gabr, Mostafa A., Jing, Liufang, Helbling, Antonia R., Sinclair, S. Michael, Allen, Kyle D., Shamji, Mohammed F., Richardson, William J., Fitch, Robert D., Setton, Lori A., Chen, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3007672/
https://ncbi.nlm.nih.gov/pubmed/20665551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.21206
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