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Engineering an efficient secretion of leech carboxypeptidase inhibitor in Escherichia coli

BACKGROUND: Despite advances in expression technologies, the efficient production of heterologous secreted proteins in Escherichia coli remains a challenge. One frequent limitation relies on their inability to be exported to the E. coli periplasm. However, recent studies have suggested that translat...

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Autors principals: Puertas, Juan-Miguel, Betton, Jean-Michel
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775724/
https://ncbi.nlm.nih.gov/pubmed/19874597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-8-57
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