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FVII, FVIIa and downstream markers of extrinsic pathway activation differ by EPCR Ser219Gly variant in healthy men
OBJECTIVE: To determine the effect of a variant in EPCR (Ser219Gly), previously shown to affect EPCR shedding, upon plasma FVII, FVIIa and downstream markers of activated coagulation. METHODS: Statistical analysis was undertaken in ~2000 healthy middle aged men (NPHSII) RESULTS: Higher soluble EPCR...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2775706/ https://ncbi.nlm.nih.gov/pubmed/19696402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.109.191551 |
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